5S9K: XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM010955a

PDB ID: 5S9KDownload
MMDB ID: 203326
PDB Deposition Date: 2021/3/25
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 1.35  Å
Source Organism:
Similar Structures:
Biological Unit for 5S9K: dimeric; determined by author and by software (PISA)
Molecular Components in 5S9K
Label Count Molecule
Proteins (2 molecules)
2
Activin Receptor Type-1
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (26 molecules)
1
4
4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine
2
13
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
6
SULFATE IONSULFATE ION
5
1
(3S)-3-aminopyrrolidin-2-one(3S)-3-aminopyrrolidin-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303