5S8A: XChem group deposition -- Crystal Structure of human ACVR1 in complex with NU074484b

PDB ID: 5S8ADownload
MMDB ID: 203324
PDB Deposition Date: 2020/12/11
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 1.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5S8A: dimeric; determined by author and by software (PISA)
Molecular Components in 5S8A
Label Count Molecule
Proteins (2 molecules)
2
Activin Receptor Type-1
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (27 molecules)
1
4
4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine
2
13
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
4
2
(4S)-imidazolidine-4-carbonitrile(4S)-imidazolidine-4-carbonitrile
5
6
SULFATE IONSULFATE ION
6
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303