5Q17: Ligand binding to FARNESOID-X-RECEPTOR

PDB ID: 5Q17Download
MMDB ID: 152457
PDB Deposition Date: 2017/5/31
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5Q17: dimeric; determined by author and by software (PISA)
Molecular Components in 5Q17
Label Count Molecule
Proteins (2 molecules)
1
Bile Acid Receptor
(Gene symbol: NR1H4)
Molecule annotation
1
Nuclear Receptor Coactivator Peptide Src2
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-({5-bromo-2-oxo-1'-[(thiophen-2-yl)sulfonyl]spiro[indole-3,4'-piperidin]-1(2H)-yl}methyl)benzoic acid4-({5-bromo-2-oxo-1'-[(thiophen-2-yl)sulfonyl]spiro[indole-3,4'-piperidin]-1(2H)-yl}methyl)benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303