5PB5: human factor VIIa in complex with 1-[[3-[5-hydroxy-4-(7H-pyrrolo[2,3-d]pyrimidin-6-yl)pyrazol-1-yl]phenyl]methyl]-3-phenylurea at 1.84A

PDB ID: 5PB5Download
MMDB ID: 151991
PDB Deposition Date: 2016/11/16
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.84  Å
Source Organism:
Similar Structures:
Biological Unit for 5PB5: dimeric; determined by author
Molecular Components in 5PB5
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor VII Light Chain
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII Heavy Chain
(Gene symbol: F7)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
GLYCEROLGLYCEROL
2
1
N-({3-[5-hydroxy-4-(7H-pyrrolo[2,3-d]pyrimidin-6-yl)-1H-pyrazol-1-yl]phenyl}methyl)-N'-phenylureaN-({3-[5-hydroxy-4-(7H-pyrrolo[2,3-d]pyrimidin-6-yl)-1H-pyrazol-1-yl]phenyl}methyl)-N'-phenylurea
3
1
CALCIUM IONCALCIUM ION
4
1
CHLORIDE IONCHLORIDE ION
5
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303