5OCA: PCSK9:Fab Complex with Dextran Sulfate

PDB ID: 5OCADownload
MMDB ID: 154617
PDB Deposition Date: 2017/6/30
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5OCA: tetrameric; determined by author and by software (PISA)
Molecular Components in 5OCA
Label Count Molecule
Proteins (4 molecules)
1
Proprotein Convertase Subtilisin/kexin Type 9
(Gene symbol: PCSK9)
Molecule annotation
1
Proprotein Convertase Subtilisin/kexin Type 9
(Gene symbol: PCSK9)
Molecule annotation
1
FAB From Ldlr Competitive Antibody: Heavy Chain
Molecule annotation
1
FAB From Ldlr Competitive Antibody: Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
[(2~{R},3~{S},4~{R},5~{R},6~{R})-2-[[(2~{S},3~{S},4~{R},5~{S},6~{R})-3,6-bis(oxidanyl)-4,5-disulfooxy-oxan-2-yl]methoxy]-6-(hydroxymethyl)-3,5-disulfooxy-oxan-4-yl] hydrogen sulfate[(2~{R},3~{S},4~{R},5~{R},6~{R})-2-[[(2~{S},3~{S},4~{R},5~{S},6~{R})-3,6-bis(oxidanyl)-4,5-disulfooxy-oxan-2-yl]methoxy]-6-(hydroxymethyl)-3,5-disulfooxy-oxan-4-yl] hydrogen sulfate
2
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303