5OBR: Aurora A kinase in complex with 2-(3-chloro-5-fluorophenyl)quinoline-4-carboxylic acid and JNJ-7706621

PDB ID: 5OBRDownload
MMDB ID: 153436
PDB Deposition Date: 2017/6/29
Updated in MMDB: 2017/09
Experimental Method:
x-ray diffraction
Resolution: 2.62  Å
Source Organism:
Similar Structures:
Biological Unit for 5OBR: monomeric; determined by software (PISA)
Molecular Components in 5OBR
Label Count Molecule
Protein (1 molecule)
1
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-(3-chloranyl-5-fluoranyl-phenyl)quinoline-4-carboxylic acid2-(3-chloranyl-5-fluoranyl-phenyl)quinoline-4-carboxylic acid
2
1
4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide
3
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303