5O4E: Crystal structure of VEGF in complex with heterodimeric Fcab JanusCT6

PDB ID: 5O4EDownload
MMDB ID: 154070
PDB Deposition Date: 2017/5/29
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 5O4E: hexameric; determined by author and by software (PISA)
Molecular Components in 5O4E
Label Count Molecule
Proteins (6 molecules)
1
Immunoglobulin Gamma-1 Heavy Chain
Molecule annotation
2
Immunoglobulin Gamma-1 Heavy Chain
Molecule annotation
1
Immunoglobulin Gamma-1 Heavy Chain
Molecule annotation
2
Vascular Endothelial Growth Factor a
(Gene symbol: VEGFA)
Molecule annotation
Chemicals and Non-standard biopolymers (38 molecules)
1
12
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
beta-D-mannopyranosebeta-D-mannopyranose
3
7
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
alpha-L-fucopyranosealpha-L-fucopyranose
5
10
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
6
1
(4R)-2-METHYLPENTANE-2,4-DIOL(4R)-2-METHYLPENTANE-2,4-DIOL
7
2
CACODYLATE IONCACODYLATE ION
8
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303