5O2B: Crystal structure of WNK3 kinase domain in a diphosphorylated state and in a complex with the inhibitor PP-121

PDB ID: 5O2BDownload
MMDB ID: 152211
PDB Deposition Date: 2017/5/19
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.038  Å
Source Organism:
Similar Structures:
Biological Unit for 5O2B: monomeric; determined by author
Molecular Components in 5O2B
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Wnk3
(Gene symbol: WNK3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
2
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303