5NPP: 2.22A STRUCTURE OF THIOPHENE2 AND GSK945237 WITH S.AUREUS DNA GYRASE AND DNA

PDB ID: 5NPPDownload
MMDB ID: 152668
PDB Deposition Date: 2017/4/18
Updated in MMDB: 2017/07
Experimental Method:
x-ray diffraction
Resolution: 2.22  Å
Source Organism:
Staphylococcus aureus subsp. aureus N315▼
Similar Structures:
Biological Unit for 5NPP: hexameric; determined by author and by software (PISA)
Molecular Components in 5NPP
Label Count Molecule
Proteins (2 molecules)
2
DNA Gyrase Subunit B,dna Gyrase Subunit B,dna Gyrase Subunit a
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*gp*cp*cp*gp*tp*ap*gp*gp*tp*ap*cp*cp*tp*ap*cp*gp*gp*cp*t)-3')
Molecule annotation
2
DNA (5'-d(*ap*gp*cp*cp*gp*tp*ap*gp*gp*tp*ap*cp*cp*tp*ap*cp*gp*gp*cp*t)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
2
MANGANESE (II) IONMANGANESE (II) ION
2
2
~{N}-[(1~{R})-2-azanyl-1-phenyl-ethyl]-5-(2-chlorophenyl)-2-methyl-thiophene-3-carboxamide~{N}-[(1~{R})-2-azanyl-1-phenyl-ethyl]-5-(2-chlorophenyl)-2-methyl-thiophene-3-carboxamide
3
9
GLYCEROLGLYCEROL
4
1
SODIUM IONSODIUM ION
5
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
6
1
(1R)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one(1R)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303