5NO1: Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI XZ407 (compound 5g)

PDB ID: 5NO1Download
MMDB ID: 153197
PDB Deposition Date: 2017/4/10
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 5NO1: octameric; determined by software (PISA)
Molecular Components in 5NO1
Label Count Molecule
Proteins (4 molecules)
4
Integrase
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*tp*tp*gp*tp*cp*ap*tp*gp*gp*ap*ap*tp*tp*tp*cp*gp*cp*a)-3')
Molecule annotation
2
DNA (5'-d(*tp*gp*cp*gp*ap*ap*ap*tp*tp*cp*cp*ap*tp*gp*ap*cp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (42 molecules)
1
6
MAGNESIUM IONMAGNESIUM ION
2
2
methyl 2-[[3-[[2,4-bis(fluoranyl)phenyl]methylcarbamoyl]-7-methoxy-1-oxidanyl-2-oxidanylidene-1,8-naphthyridin-4-yl]amino]ethanoatemethyl 2-[[3-[[2,4-bis(fluoranyl)phenyl]methylcarbamoyl]-7-methoxy-1-oxidanyl-2-oxidanylidene-1,8-naphthyridin-4-yl]amino]ethanoate
3
2
ZINC IONZINC ION
4
16
SULFATE IONSULFATE ION
5
12
GLYCEROLGLYCEROL
6
2
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
7
2
HEXANE-1,6-DIOLHEXANE-1,6-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303