5NN5: Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with 1-deoxynojirimycin

PDB ID: 5NN5Download
MMDB ID: 155325
PDB Deposition Date: 2017/4/8
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 5NN5: monomeric; determined by software (PISA)
Molecular Components in 5NN5
Label Count Molecule
Protein (1 molecule)
1
Lysosomal Alpha-glucosidase
(Gene symbol: GAA)
Molecule annotation
Chemicals and Non-standard biopolymers (33 molecules)
1
10
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
alpha-L-fucopyranosealpha-L-fucopyranose
3
2
beta-D-mannopyranosebeta-D-mannopyranose
4
1
alpha-D-mannopyranosealpha-D-mannopyranose
5
1
1-DEOXYNOJIRIMYCIN1-DEOXYNOJIRIMYCIN
6
4
SULFATE IONSULFATE ION
7
6
CHLORIDE IONCHLORIDE ION
8
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303