5NKY: Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain

PDB ID: 5NKYDownload
MMDB ID: 151069
PDB Deposition Date: 2017/4/3
Updated in MMDB: 2017/09
Experimental Method:
x-ray diffraction
Resolution: 2.096  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 5NKY: tetrameric; determined by author and by software (PISA)
Molecular Components in 5NKY
Label Count Molecule
Proteins (4 molecules)
2
Vitamin D3 Receptor a
Molecule annotation
2
Src1
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-7~{a}-methyl-1-[(1~{S})-1-[(2~{R},5~{S})-5-(2-oxidanylpropan-2-yl)oxolan-2-yl]ethyl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol(1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-7~{a}-methyl-1-[(1~{S})-1-[(2~{R},5~{S})-5-(2-oxidanylpropan-2-yl)oxolan-2-yl]ethyl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303