5NGS: Crystal structure of human MTH1 in complex with inhibitor 6-[(2-phenylethyl)sulfanyl]-7H-purin-2-amine

PDB ID: 5NGSDownload
MMDB ID: 154924
PDB Deposition Date: 2017/3/20
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 5NGS: monomeric; determined by author
Molecular Components in 5NGS
Label Count Molecule
Protein (1 molecule)
1
7,8-dihydro-8-oxoguanine Triphosphatase
(Gene symbol: NUDT1)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
6-(2-phenylethylsulfanyl)-7~{H}-purin-2-amine6-(2-phenylethylsulfanyl)-7~{H}-purin-2-amine
2
7
SULFATE IONSULFATE ION
3
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303