5NGE: Crystal structure of USP7 in complex with the non-covalent inhibitor, FT671

PDB ID: 5NGEDownload
MMDB ID: 155058
PDB Deposition Date: 2017/3/17
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 5NGE: monomeric; determined by author and by software (PISA)
Molecular Components in 5NGE
Label Count Molecule
Protein (1 molecule)
1
Ubiquitin Carboxyl-terminal Hydrolase 7
(Gene symbol: USP7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[[1-[(3~{S})-4,4-bis(fluoranyl)-3-(3-fluoranylpyrazol-1-yl)butanoyl]-4-oxidanyl-piperidin-4-yl]methyl]-1-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-4-one5-[[1-[(3~{S})-4,4-bis(fluoranyl)-3-(3-fluoranylpyrazol-1-yl)butanoyl]-4-oxidanyl-piperidin-4-yl]methyl]-1-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303