5NG5: multi-drug efflux; membrane transport; RND superfamily; Drug resistance

PDB ID: 5NG5Download
MMDB ID: 149940
PDB Deposition Date: 2017/3/16
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 6.5  Å
Source Organism:
Similar Structures:
Biological Unit for 5NG5: 15-meric; determined by author and by software (PISA)
Molecular Components in 5NG5
Label Count Molecule
Proteins (15 molecules)
6
Multidrug Efflux Pump Subunit Acra
Molecule annotation
3
Outer Membrane Protein Tolc
Molecule annotation
3
Multidrug Efflux Pump Subunit Acrb
Molecule annotation
3
Multidrug Efflux Pump Accessory Protein Acrz
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303