5N8V: Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases

PDB ID: 5N8VDownload
MMDB ID: 148116
PDB Deposition Date: 2017/2/24
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 5N8V: monomeric; determined by author and by software (PISA)
Molecular Components in 5N8V
Label Count Molecule
Protein (1 molecule)
1
Peroxin 14
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
1-(2-azanylethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide1-(2-azanylethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide
2
3
SULFATE IONSULFATE ION
3
1
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
4
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303