5N8C: Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor

PDB ID: 5N8CDownload
MMDB ID: 149101
PDB Deposition Date: 2017/2/23
Updated in MMDB: 2017/04
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5N8C: monomeric; determined by author
Molecular Components in 5N8C
Label Count Molecule
Protein (1 molecule)
1
Udp-3-o-acyl-n-acetylglucosamine Deacetylase
(Gene symbol: lpxC)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
ZINC IONZINC ION
2
1
(2~{S})-3-azanyl-2-[[(1~{R})-5-[2-[4-[[2-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]ethynyl]-2,3-dihydro-1~{H}-inden-1-yl]amino]-3-methyl-~{N}-oxidanyl-butanamide(2~{S})-3-azanyl-2-[[(1~{R})-5-[2-[4-[[2-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]ethynyl]-2,3-dihydro-1~{H}-inden-1-yl]amino]-3-methyl-~{N}-oxidanyl-butanamide
3
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303