5N20: Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand

PDB ID: 5N20Download
MMDB ID: 150839
PDB Deposition Date: 2017/2/6
Updated in MMDB: 2017/06
Experimental Method:
x-ray diffraction
Resolution: 1.38  Å
Source Organism:
Similar Structures:
Biological Unit for 5N20: dimeric; determined by software (PISA)
Molecular Components in 5N20
Label Count Molecule
Proteins (2 molecules)
2
B-cell Lymphoma 6 Protein
(Gene symbol: BCL6)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
~{N}-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[(3~{R})-3-(dimethylamino)pyrrolidin-1-yl]phenyl]ethanamide~{N}-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[(3~{R})-3-(dimethylamino)pyrrolidin-1-yl]phenyl]ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303