5MQF: Cryo-em Structure Of A Human Spliceosome Activated For Step 2 Of Splicing (c* Complex)

PDB ID: 5MQFDownload
MMDB ID: 148556
PDB Deposition Date: 2016/12/20
Updated in MMDB: 2017/09
Experimental Method:
electron microscopy
Resolution: 5.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5MQF: 46-meric; determined by software (PISA)
Molecular Components in 5MQF
Label Count Molecule
Proteins (41 molecules)
1
Pre-mrna-processing-splicing Factor 8(Gene symbol: PRPF8)
Molecule annotation
1
116 KDA U5 Small Nuclear Ribonucleoprotein Component(Gene symbol: EFTUD2)
Molecule annotation
1
SNW Domain-containing Protein 1(Gene symbol: SNW1)
Molecule annotation
1
Pleiotropic Regulator 1(Gene symbol: PLRG1)
Molecule annotation
1
Pre-mrna-processing Factor 17(Gene symbol: CDC40)
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 40 KDA Protein(Gene symbol: SNRNP40)
Molecule annotation
4
Pre-mrna-processing Factor 19(Gene symbol: PRPF19)
Molecule annotation
1
Pre-mrna-splicing Factor Spf27(Gene symbol: BCAS2)
Molecule annotation
1
Cell Division Cycle 5-like Protein(Gene symbol: CDC5L)
Molecule annotation
1
Pre-mrna-splicing Factor Syf1(Gene symbol: XAB2)
Molecule annotation
1
Pre-mrna-splicing Factor Syf2(Gene symbol: SYF2)
Molecule annotation
1
Crooked Neck-like Protein 1(Gene symbol: CRNKL1)
Molecule annotation
1
Pre-mrna-splicing Factor Rbm22(Gene symbol: RBM22)
Molecule annotation
1
Protein Bud31 Homolog(Gene symbol: BUD31)
Molecule annotation
1
Spliceosome-associated Protein Cwc15 Homolog(Gene symbol: CWC15)
Molecule annotation
1
Serine/arginine Repetitive Matrix Protein 2(Gene symbol: SRRM2)
Molecule annotation
1
Pre-mrna-splicing Factor Cwc22 Homolog(Gene symbol: CWC22)
Molecule annotation
1
Intron-binding Protein Aquarius(Gene symbol: AQR)
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase-like 1(Gene symbol: PPIL1)
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein A'(Gene symbol: SNRPA1)
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein B''(Gene symbol: SNRPB2)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D2(Gene symbol: SNRPD2)
Molecule annotation
2
Small Nuclear Ribonucleoprotein F(Gene symbol: SNRPF)
Molecule annotation
2
Small Nuclear Ribonucleoprotein E(Gene symbol: SNRPE)
Molecule annotation
2
Small Nuclear Ribonucleoprotein G(Gene symbol: SNRPG)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D3(Gene symbol: SNRPD3)
Molecule annotation
2
Small Nuclear Ribonucleoprotein-associated Proteins B and B'(Gene symbol: SNRPB)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D1(Gene symbol: SNRPD1)
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase E(Gene symbol: PPIE)
Molecule annotation
1
Eukaryotic Initiation Factor 4a-iii(Gene symbol: EIF4A3)
Molecule annotation
1
Atp-dependent RNA Helicase Dhx8(Gene symbol: DHX8)
Molecule annotation
Nucleotides(4 molecules)
2
Minx Pre-mrna (Intron)
Molecule annotation
1
Human Gene for Small Nuclear RNA U2 (Snrna U2)
Molecule annotation
1
Homo Sapiens U5 a Small Nuclear RNA
Molecule annotation
1
Homo Sapiens RNA, U6 Small Nuclear 1 (Rnu6-1), Small Nuclear RNA
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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