5MMB: Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI XZ434 (compound 6p)

PDB ID: 5MMBDownload
MMDB ID: 153181
PDB Deposition Date: 2016/12/9
Updated in MMDB: 2020/10
Experimental Method:
x-ray diffraction
Resolution: 2.77  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 5MMB: octameric; determined by author and by software (PISA)
Molecular Components in 5MMB
Label Count Molecule
Proteins (4 molecules)
4
PFV Integrase
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*tp*tp*gp*tp*cp*ap*tp*gp*gp*ap*ap*tp*tp*tp*cp*gp*cp*a)-3')
Molecule annotation
2
DNA (5'-d(*tp*gp*cp*gp*ap*ap*ap*tp*tp*cp*cp*ap*tp*gp*ap*cp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (48 molecules)
1
2
ZINC IONZINC ION
2
6
MAGNESIUM IONMAGNESIUM ION
3
18
SULFATE IONSULFATE ION
4
14
GLYCEROLGLYCEROL
5
2
methyl 3-[5-azanyl-6-[[2,4-bis(fluoranyl)phenyl]methylcarbamoyl]-8-oxidanyl-7-oxidanylidene-1,8-naphthyridin-3-yl]propanoatemethyl 3-[5-azanyl-6-[[2,4-bis(fluoranyl)phenyl]methylcarbamoyl]-8-oxidanyl-7-oxidanylidene-1,8-naphthyridin-3-yl]propanoate
6
6
HEXANE-1,6-DIOLHEXANE-1,6-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303