5MJU: Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101

PDB ID: 5MJUDownload
MMDB ID: 149917
PDB Deposition Date: 2016/12/1
Updated in MMDB: 2017/05
Experimental Method:
x-ray diffraction
Resolution: 3.71  Å
Source Organism:
Similar Structures:
Biological Unit for 5MJU: trimeric; determined by author and by software (PISA)
Molecular Components in 5MJU
Label Count Molecule
Proteins (3 molecules)
3
Excitatory Amino Acid Transporter 1,neutral Amino Acid Transporter B(0),excitatory Amino Acid Transporter 1
(Gene symbol: SLC1A3)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
3
2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile
2
3
(2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic acid(2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303