5MJ6: Ligand-induced conformational change of Insulin-regulated aminopeptidase: insights on catalytic mechanism and active site plasticity

PDB ID: 5MJ6Download
MMDB ID: 149525
PDB Deposition Date: 2016/11/30
Updated in MMDB: 2017/04
Experimental Method:
x-ray diffraction
Resolution: 2.53  Å
Source Organism:
Similar Structures:
Biological Unit for 5MJ6: monomeric; determined by author
Molecular Components in 5MJ6
Label Count Molecule
Protein (1 molecule)
1
Leucyl-cystinyl Aminopeptidase
(Gene symbol: LNPEP)
Molecule annotation
Chemicals and Non-standard biopolymers (54 molecules)
1
31
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
alpha-D-mannopyranosealpha-D-mannopyranose
3
5
beta-D-mannopyranosebeta-D-mannopyranose
4
1
ZINC IONZINC ION
5
1
[(2~{S})-2-[[(2~{S})-1-azanyl-1-oxidanylidene-3-phenyl-propan-2-yl]carbamoyl]-4,4-diphenyl-butyl]-[(1~{R})-1-azanyl-3-phenyl-propyl]phosphinic acid[(2~{S})-2-[[(2~{S})-1-azanyl-1-oxidanylidene-3-phenyl-propan-2-yl]carbamoyl]-4,4-diphenyl-butyl]-[(1~{R})-1-azanyl-3-phenyl-propyl]phosphinic acid
6
12
BROMIDE IONBROMIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303