5MIM: Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n

PDB ID: 5MIMDownload
MMDB ID: 150657
PDB Deposition Date: 2016/11/28
Updated in MMDB: 2017/06
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5MIM: monomeric; determined by author and by software (PISA)
Molecular Components in 5MIM
Label Count Molecule
Protein (1 molecule)
1
Furin
(Gene symbol: FURIN)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
3
CALCIUM IONCALCIUM ION
2
4
SODIUM IONSODIUM ION
3
1
CHLORIDE IONCHLORIDE ION
4
2
1-[(1~{R},2~{R},4~{S},5~{S})-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine1-[(1~{R},2~{R},4~{S},5~{S})-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303