National Center for
Biotechnology Information

5MEV: MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 21

PDB ID:

MMDB ID:

147998

PDB Deposition Date:

2016/11/16

Updated in MMDB:

2018/12

Experimental Method:

x-ray diffraction

Resolution:

2.94 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	A
Homo sapiens	H, L

Similar Structures:

Biological Unit for 5MEV: trimeric; determined by author and by software (PISA)

Molecular Components in 5MEV
Label	Count	Molecule
Proteins (3 molecules)
A	1	Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 Homolog,induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
H	1	FAB Heavy Chain
L	1	FAB Light Chain
Chemical and Non-standard biopolymers (1 molecule)
1	1	(5~{R},13~{S},17~{S})-5-[(3,4-dichlorophenyl)methyl]-8-methyl-13-[(4-methylsulfonylphenyl)methyl]-1,4,8,12,16-pentazatricyclo[15.8.1.0^{20,25}]hexacosa-20,22,24-triene-3,7,15,26-tetrone $(5~{R},13~{S},17~{S})-5-[(3,4-dichlorophenyl)methyl]-8-methyl-13-[(4-methylsulfonylphenyl)methyl]-1,4,8,12,16-pentazatricyclo[15.8.1.0^{20,25}]hexacosa-20,22,24-triene-3,7,15,26-tetrone$

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Citing MMDB