5MCQ: CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH ACTIVE SITE AND EXOSITE BINDING PEPTIDE INHIBITOR

PDB ID: 5MCQDownload
MMDB ID: 154745
PDB Deposition Date: 2016/11/10
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 1.82  Å
Source Organism:
Similar Structures:
Biological Unit for 5MCQ: dimeric; determined by author and by software (PISA)
Molecular Components in 5MCQ
Label Count Molecule
Proteins (2 molecules)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
1
Bace-1 Active and Exosite Binding Inhibitor
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303