5M53: Nek2 bound to arylaminopurine inhibitor 11

PDB ID: 5M53Download
MMDB ID: 144842
PDB Deposition Date: 2016/10/20
Updated in MMDB: 2016/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5M53: monomeric; determined by author and by software (PISA)
Molecular Components in 5M53
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Nek2
(Gene symbol: NEK2)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
1
3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N},~{N}-dimethyl-benzamide3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N},~{N}-dimethyl-benzamide
2
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
4
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303