5LZ4: Fragment-based inhibitors of Lipoprotein associated Phospholipase A2

PDB ID: 5LZ4Download
MMDB ID: 246774
PDB Deposition Date: 2016/9/29
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.07  Å
Source Organism:
Similar Structures:
Biological Unit for 5LZ4: monomeric; determined by software (PISA)
Molecular Components in 5LZ4
Label Count Molecule
Protein (1 molecule)
1
Platelet-activating Factor Acetylhydrolase
(Gene symbol: PLA2G7)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
1
5-[2-(4,4-dimethyl-2-oxidanylidene-pyrrolidin-1-yl)ethoxy]-2-fluoranyl-benzenecarbonitrile5-[2-(4,4-dimethyl-2-oxidanylidene-pyrrolidin-1-yl)ethoxy]-2-fluoranyl-benzenecarbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303