5LYQ: Crystal structure of the Retinoic Acid Receptor alpha in complex with a synthetic spiroketal agonist and a fragment of the TIF2 co-activator

PDB ID: 5LYQDownload
MMDB ID: 150108
PDB Deposition Date: 2016/9/28
Updated in MMDB: 2017/09
Experimental Method:
x-ray diffraction
Resolution: 2.17  Å
Source Organism:
Similar Structures:
Biological Unit for 5LYQ: tetrameric; determined by author
Molecular Components in 5LYQ
Label Count Molecule
Proteins (4 molecules)
2
Retinoic Acid Receptor Rxr-alpha
(Gene symbol: RXRA)
Molecule annotation
2
His-lys-ile-leu-his-arg-leu-leu-gln-asp
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(2~{R})-6,6,9,9-tetramethylspiro[3,4,7,8-tetrahydrobenzo[g]chromene-2,2'-3,4-dihydrochromene]-6'-carboxylic acid(2~{R})-6,6,9,9-tetramethylspiro[3,4,7,8-tetrahydrobenzo[g]chromene-2,2'-3,4-dihydrochromene]-6'-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303