5LPM: Crystal structure of the bromodomain of human Ep300 bound to the inhibitor XDM3d

PDB ID: 5LPMDownload
MMDB ID: 153623
PDB Deposition Date: 2016/8/13
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 5LPM: monomeric; determined by author
Molecular Components in 5LPM
Label Count Molecule
Protein (1 molecule)
1
Histone Acetyltransferase P300
(Gene symbol: EP300)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
~{N}-[(1~{S},2~{S})-7-chloranyl-2-oxidanyl-1,2,3,4-tetrahydronaphthalen-1-yl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole -2-carboxamide~{N}-[(1~{S},2~{S})-7-chloranyl-2-oxidanyl-1,2,3,4-tetrahydronaphthalen-1-yl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole -2-carboxamide
2
3
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303