5LPK: Crystal structure of the bromodomain of human EP300 bound to the inhibitor XDM1

PDB ID: 5LPKDownload
MMDB ID: 153621
PDB Deposition Date: 2016/8/13
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5LPK: monomeric; determined by author
Molecular Components in 5LPK
Label Count Molecule
Protein (1 molecule)
1
Histone Acetyltransferase P300
(Gene symbol: EP300)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
~{N}-[(3-chlorophenyl)methyl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole-2-carboxamide~{N}-[(3-chlorophenyl)methyl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole-2-carboxamide
2
2
SULFATE IONSULFATE ION
3
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303