5LPD: Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(2-(aminomethyl)-5-chlorobenzyl) pyrrolidine-2-carboxamide

PDB ID: 5LPDDownload
MMDB ID: 152962
PDB Deposition Date: 2016/8/12
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 5LPD: trimeric; determined by author and by software (PISA)
Molecular Components in 5LPD
Label Count Molecule
Proteins (3 molecules)
1
Thrombin Light Chain
Molecule annotation
1
Thrombin Heavy Chain
Molecule annotation
1
Hirudin Variant-2
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
SODIUM IONSODIUM ION
3
1
PHOSPHATE IONPHOSPHATE ION
4
1
GLYCEROLGLYCEROL
5
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
6
1
(2~{S})-~{N}-[[2-(aminomethyl)-5-chloranyl-phenyl]methyl]-1-[(2~{R})-2-azanyl-3-cyclohexyl-propanoyl]pyrrolidine-2-carboxamide(2~{S})-~{N}-[[2-(aminomethyl)-5-chloranyl-phenyl]methyl]-1-[(2~{R})-2-azanyl-3-cyclohexyl-propanoyl]pyrrolidine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303