5LM4: Structure of the thermostalilized EAAT1 cryst-II mutant in complex with L-ASP and the allosteric inhibitor UCPH101

PDB ID: 5LM4Download
MMDB ID: 149902
PDB Deposition Date: 2016/7/29
Updated in MMDB: 2017/05
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5LM4: monomeric; determined by author
Molecular Components in 5LM4
Label Count Molecule
Protein (1 molecule)
1
Excitatory Amino Acid Transporter 1,neutral Amino Acid Transporter B(0),excitatory Amino Acid Transporter 1
(Gene symbol: SLC1A3)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
SODIUM IONSODIUM ION
2
1
ASPARTIC ACIDASPARTIC ACID
3
1
2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303