5LHQ: The EGR-cmk active site inhibited catalytic domain of murine urokinase-type plasminogen activator in complex with the allosteric inhibitory nanobody Nb7

PDB ID: 5LHQDownload
MMDB ID: 152139
PDB Deposition Date: 2016/7/12
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Vicugna pacos▼
Similar Structures:
Biological Unit for 5LHQ: dimeric; determined by author and by software (PISA)
Molecular Components in 5LHQ
Label Count Molecule
Proteins (2 molecules)
1
Urokinase-type Plasminogen Activator
Molecule annotation
1
Camelid-derived Antibody Fragment NB7
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
1
L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamideL-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide
2
11
SULFATE IONSULFATE ION
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303