5LGO: Trypsin inhibitors for the treatment of pancreatitis - cpd 15

PDB ID: 5LGODownload
MMDB ID: 142228
PDB Deposition Date: 2016/7/7
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.12  Å
Source Organism:
Similar Structures:
Biological Unit for 5LGO: monomeric; determined by software (PISA)
Molecular Components in 5LGO
Label Count Molecule
Protein (1 molecule)
1
Cationic Trypsin
(Gene symbol: PRSS1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
1
CALCIUM IONCALCIUM ION
3
1
(2~{S},4~{S})-1-[4-(aminomethyl)-3-methoxy-phenyl]carbonyl-4-[4-(2-cyclopropylethoxy)-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidin-7-yl]-~{N}-methyl-pyrrolidine-2-carboxamide(2~{S},4~{S})-1-[4-(aminomethyl)-3-methoxy-phenyl]carbonyl-4-[4-(2-cyclopropylethoxy)-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidin-7-yl]-~{N}-methyl-pyrrolidine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303