5LCJ: In-gel Activity-based Protein Profiling Of A Clickable Covalent Erk 1/2 Inhibitor

PDB ID: 5LCJDownload
MMDB ID: 140857
PDB Deposition Date: 2016/6/22
Updated in MMDB: 2016/09
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 5LCJ: monomeric; determined by software (PISA)
Molecular Components in 5LCJ
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 1
(Gene symbol: MAPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
[(1~{r},4~{z})-Cyclooct-4-En-1-Yl] ~{n}-[4-[4-[[5-Chloranyl-4-[[2-(Propanoylamino)phenyl]amino]pyrimidin-2-Yl]amino]pyridin-2-Yl]but-3-Ynyl]carbamate[(1~{r},4~{z})-Cyclooct-4-En-1-Yl] ~{n}-[4-[4-[[5-Chloranyl-4-[[2-(Propanoylamino)phenyl]amino]pyrimidin-2-Yl]amino]pyridin-2-Yl]but-3-Ynyl]carbamate
2
2
Sulfate IonSulfate Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303