5LCE: Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(5-chloro-2-(hydroxymethyl)benzy l)pyrrolidine-2-carboxamide

PDB ID: 5LCEDownload
MMDB ID: 152959
PDB Deposition Date: 2016/6/21
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.39  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 5LCE: trimeric; determined by author and by software (PISA)
Molecular Components in 5LCE
Label Count Molecule
Proteins (3 molecules)
1
Prothrombin
Molecule annotation
1
Prothrombin
Molecule annotation
1
Hirudin Variant-2
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
(2~{S})-1-[(2~{R})-2-azanyl-3-cyclohexyl-propanoyl]-~{N}-[[5-chloranyl-2-(hydroxymethyl)phenyl]methyl]pyrrolidine-2-carboxamide(2~{S})-1-[(2~{R})-2-azanyl-3-cyclohexyl-propanoyl]-~{N}-[[5-chloranyl-2-(hydroxymethyl)phenyl]methyl]pyrrolidine-2-carboxamide
2
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
1
PHOSPHATE IONPHOSPHATE ION
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
2
SODIUM IONSODIUM ION
6
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
7
3
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303