5LBF: HIF prolyl hydroxylase 2 (PHD2/EGLN1) K293K/G294E variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/FG2216)

PDB ID: 5LBFDownload
MMDB ID: 142684
PDB Deposition Date: 2016/6/16
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.8995  Å
Source Organism:
Similar Structures:
Biological Unit for 5LBF: monomeric; determined by software (PISA)
Molecular Components in 5LBF
Label Count Molecule
Protein (1 molecule)
1
EGL Nine Homolog 1
(Gene symbol: EGLN1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINEN-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
3
2
SULFATE IONSULFATE ION
4
1
BICARBONATE IONBICARBONATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303