5LAS: HIF prolyl hydroxylase 2 (PHD2-R281C/P317C/R396T) cross-linked to HIF-1alpha NODD-L397C/D412C and N-oxalylglycine (NOG) (complex-3)

PDB ID: 5LASDownload
MMDB ID: 142678
PDB Deposition Date: 2016/6/14
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5LAS: tetrameric; determined by author and by software (PISA)
Molecular Components in 5LAS
Label Count Molecule
Proteins (4 molecules)
2
EGL Nine Homolog 1
(Gene symbol: EGLN1)
Molecule annotation
2
Hypoxia-inducible Factor 1-alpha
(Gene symbol: HIF1A)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
MANGANESE (II) IONMANGANESE (II) ION
2
2
N-OXALYLGLYCINEN-OXALYLGLYCINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303