5LA9: HIF prolyl hydroxylase 2 (PHD2-R281C/V314C) cross-linked to HIF-1alpha NODD-L397C/D412C and N-oxalylglycine (NOG) (complex-2)

PDB ID: 5LA9Download
MMDB ID: 142677
PDB Deposition Date: 2016/6/14
Updated in MMDB: 2016/09
Experimental Method:
x-ray diffraction
Resolution: 2.813  Å
Source Organism:
Similar Structures:
Biological Unit for 5LA9: dimeric; determined by author and by software (PISA)
Molecular Components in 5LA9
Label Count Molecule
Proteins (2 molecules)
1
EGL Nine Homolog 1
(Gene symbol: EGLN1)
Molecule annotation
1
Hypoxia-inducible Factor 1-alpha
(Gene symbol: HIF1A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
N-OXALYLGLYCINEN-OXALYLGLYCINE
3
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303