5L9Y: Crystal structure of human heparanase, in complex with glucuronic acid configured aziridine probe JJB355

PDB ID: 5L9YDownload
MMDB ID: 151264
PDB Deposition Date: 2016/6/13
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.88  Å
Source Organism:
Similar Structures:
Biological Unit for 5L9Y: dimeric; determined by author and by software (PISA)
Molecular Components in 5L9Y
Label Count Molecule
Proteins (2 molecules)
1
Heparanase
(Gene symbol: HPSE)
Molecule annotation
1
Heparanase
(Gene symbol: HPSE)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
alpha-L-fucopyranosealpha-L-fucopyranose
3
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
(1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid(1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303