5L8A: Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases

PDB ID: 5L8ADownload
MMDB ID: 147909
PDB Deposition Date: 2016/6/7
Updated in MMDB: 2017/04
Experimental Method:
x-ray diffraction
Resolution: 1.57  Å
Source Organism:
Similar Structures:
Biological Unit for 5L8A: monomeric; determined by author
Molecular Components in 5L8A
Label Count Molecule
Protein (1 molecule)
1
Peroxin 14
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(phenylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(phenylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide
2
1
GLYCINEGLYCINE
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303