5L7I: Structure of human Smoothened in complex with Vismodegib

PDB ID: 5L7IDownload
MMDB ID: 140852
PDB Deposition Date: 2016/6/3
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5L7I: monomeric; determined by author
Molecular Components in 5L7I
Label Count Molecule
Protein (1 molecule)
1
Smoothened Homolog,soluble Cytochrome B562,smoothened Homolog
(Gene symbol: SMO)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide
3
2
[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303