5L6J: Uba1 in complex with Ub-MLN7243 covalent adduct

PDB ID: 5L6JDownload
MMDB ID: 151702
PDB Deposition Date: 2016/5/30
Updated in MMDB: 2017/09
Experimental Method:
x-ray diffraction
Resolution: 2.68  Å
Source Organism:
Similar Structures:
Biological Unit for 5L6J: dimeric; determined by author and by software (PISA)
Molecular Components in 5L6J
Label Count Molecule
Proteins (2 molecules)
1
Ubiquitin-activating Enzyme E1 1
(Gene symbol: UBA1)
Molecule annotation
1
Ubiquitin-40s Ribosomal Protein S31
(Gene symbol: RPS31)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
SULFATE IONSULFATE ION
2
2
CHLORIDE IONCHLORIDE ION
3
7
GLYCEROLGLYCEROL
4
1
[(1~{R},2~{R},3~{S},4~{R})-2,3-bis(oxidanyl)-4-[[2-[3-(trifluoromethylsulfanyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]cyclopentyl]methyl sulfamate[(1~{R},2~{R},3~{S},4~{R})-2,3-bis(oxidanyl)-4-[[2-[3-(trifluoromethylsulfanyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]cyclopentyl]methyl sulfamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303