5L6D: Crystal structure of the human METTL3-METTL14 complex bound to SAH

PDB ID: 5L6DDownload
MMDB ID: 144019
PDB Deposition Date: 2016/5/29
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.852  Å
Source Organism:
Similar Structures:
Biological Unit for 5L6D: dimeric; determined by author and by software (PISA)
Molecular Components in 5L6D
Label Count Molecule
Proteins (2 molecules)
1
N6-adenosine-methyltransferase 70 KDA Subunit
(Gene symbol: METTL3)
Molecule annotation
1
N6-adenosine-methyltransferase Subunit Mettl14
(Gene symbol: METTL14)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303