5L3E: LSD1-CoREST1 in complex with quinazoline-derivative reversible inhibitor

PDB ID: 5L3EDownload
MMDB ID: 143371
PDB Deposition Date: 2016/4/10
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5L3E: dimeric; determined by author and by software (PISA)
Molecular Components in 5L3E
Label Count Molecule
Proteins (2 molecules)
1
Lysine-specific Histone Demethylase 1A
(Gene symbol: KDM1A)
Molecule annotation
1
Rest Corepressor 1
(Gene symbol: RCOR1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
2
5
N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6,7-dimethoxyquinazoline-2,4-diamineN~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6,7-dimethoxyquinazoline-2,4-diamine
3
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303