5L0H: Human metavinculin MVt cardiomyopathy-associated mutant R975W (residues 959-1134) in complex with PIP2

PDB ID: 5L0HDownload
MMDB ID: 142659
PDB Deposition Date: 2016/7/27
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5L0H: monomeric; determined by author and by software (PISA)
Molecular Components in 5L0H
Label Count Molecule
Protein (1 molecule)
1
Vinculin
(Gene symbol: VCL)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
2
1
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
3
2
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303