5KNQ: Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Guanin-9-yl)pyrrolidin-3-yl)oxymethanephosphonic acid and pyrophosphate

PDB ID: 5KNQDownload
MMDB ID: 154552
PDB Deposition Date: 2016/6/28
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.553  Å
Source Organism:
Similar Structures:
Biological Unit for 5KNQ: tetrameric; determined by author
Molecular Components in 5KNQ
Label Count Molecule
Proteins (4 molecules)
4
Hypoxanthine-guanine Phosphoribosyltransferase
(Gene symbol: hpt)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
[(3~{S},4~{R})-4-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)pyrrolidin-3-yl]oxymethylphosphonic acid[(3~{S},4~{R})-4-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)pyrrolidin-3-yl]oxymethylphosphonic acid
2
8
MAGNESIUM IONMAGNESIUM ION
3
4
PYROPHOSPHATE 2-PYROPHOSPHATE 2-
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303