5KIR: The Structure of Vioxx Bound to Human COX-2

PDB ID: 5KIRDownload
MMDB ID: 143575
PDB Deposition Date: 2016/6/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.697  Å
Source Organism:
Similar Structures:
Biological Unit for 5KIR: dimeric; determined by author and by software (PISA)
Molecular Components in 5KIR
Label Count Molecule
Proteins (2 molecules)
2
Prostaglandin G/H Synthase 2
(Gene symbol: PTGS2)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
6
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
alpha-D-mannopyranosealpha-D-mannopyranose
3
2
RofecoxibRofecoxib
4
2
PROTOPORPHYRIN IX CONTAINING COPROTOPORPHYRIN IX CONTAINING CO
5
2
AMMONIUM IONAMMONIUM ION
6
1
GLYCEROLGLYCEROL
7
6
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303