5KE2: Crystal structure of SETDB1 Tudor domain in complex with inhibitor XST06472A

PDB ID: 5KE2Download
MMDB ID: 141198
PDB Deposition Date: 2016/6/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.56  Å
Source Organism:
Similar Structures:
Biological Unit for 5KE2: monomeric; determined by author and by software (PISA)
Molecular Components in 5KE2
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase Setdb1
(Gene symbol: SETDB1)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
1
(3~{S})-~{N}-~{tert}-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide(3~{S})-~{N}-~{tert}-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
6
SULFATE IONSULFATE ION
4
8
Molecule information is not available.
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303