5K8X: Crystal structure of mouse CARM1 in complex with inhibitor U3

PDB ID: 5K8XDownload
MMDB ID: 151870
PDB Deposition Date: 2016/5/31
Updated in MMDB: 2018/06
Experimental Method:
x-ray diffraction
Resolution: 1.991  Å
Source Organism:
Similar Structures:
Biological Unit for 5K8X: tetrameric; determined by author and by software (PISA)
Molecular Components in 5K8X
Label Count Molecule
Proteins (4 molecules)
4
Histone-arginine Methyltransferase Carm1
(Gene symbol: Carm1)
Molecule annotation
Chemicals and Non-standard biopolymers (32 molecules)
1
4
[[[(~{E})-3-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]prop-2-enyl]amino]-azanyl-methylidene]azanium[[[(~{E})-3-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]prop-2-enyl]amino]-azanyl-methylidene]azanium
2
14
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
5
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
5
1
3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL
6
6
1,2-DIMETHOXYETHANE1,2-DIMETHOXYETHANE
7
1
1-METHOXY-2-(2-METHOXYETHOXY)ETHANE1-METHOXY-2-(2-METHOXYETHOXY)ETHANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303